chEnv TTT protein in complex with 43A2 Fab
Del Moral-Sanchez I, Wee EG, Xian Y, Lee WH, Allen JD, Torrents de la Pena A, Froes Rocha R, Ferguson J, Leon AN, Koekkoek S, Schermer EE, Burger JA, Kumar S, Zwolsman R, Brinkkemper M, Aartse A, Eggink D, Han J, Yuan M, Crispin M, Ozorowski G, Ward AB, Wilson IA, Hanke T, Sliepen K, Sanders RW
NPJ Vaccines (2024) 9 pp. 74-74 [ Pubmed: 38582771 DOI: doi:10.1038/s41541-024-00862-8 ]
chEnv TTT protein in complex with CM01A Fab
Del Moral-Sanchez I, Wee EG, Xian Y, Lee WH, Allen JD, Torrents de la Pena A, Froes Rocha R, Ferguson J, Leon AN, Koekkoek S, Schermer EE, Burger JA, Kumar S, Zwolsman R, Brinkkemper M, Aartse A, Eggink D, Han J, Yuan M, Crispin M, Ozorowski G, Ward AB, Wilson IA, Hanke T, Sliepen K, Sanders RW
NPJ Vaccines (2024) 9 pp. 74-74 [ Pubmed: 38582771 DOI: doi:10.1038/s41541-024-00862-8 ]
Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines
Del Moral-Sanchez I, Wee EG, Xian Y, Lee WH, Allen JD, Torrents de la Pena A, Froes Rocha R, Ferguson J, Leon AN, Koekkoek S, Schermer EE, Burger JA, Kumar S, Zwolsman R, Brinkkemper M, Aartse A, Eggink D, Han J, Yuan M, Crispin M, Ozorowski G, Ward AB, Wilson IA, Hanke T, Sliepen K, Sanders RW
NPJ Vaccines (2024) 9 pp. 74-74 [ Pubmed: 38582771 DOI: doi:10.1038/s41541-024-00862-8 ]
Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines (cH125 TTT)
Del Moral-Sanchez I, Wee EG, Xian Y, Lee WH, Allen JD, Torrents de la Pena A, Froes Rocha R, Ferguson J, Leon AN, Koekkoek S, Schermer EE, Burger JA, Kumar S, Zwolsman R, Brinkkemper M, Aartse A, Eggink D, Han J, Yuan M, Crispin M, Ozorowski G, Ward AB, Wilson IA, Hanke T, Sliepen K, Sanders RW
NPJ Vaccines (2024) 9 pp. 74-74 [ Pubmed: 38582771 DOI: doi:10.1038/s41541-024-00862-8 ]
Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines (H2/1 GCN4)
Del Moral-Sanchez I, Wee EG, Xian Y, Lee WH, Allen JD, Torrents de la Pena A, Froes Rocha R, Ferguson J, Leon AN, Koekkoek S, Schermer EE, Burger JA, Kumar S, Zwolsman R, Brinkkemper M, Aartse A, Eggink D, Han J, Yuan M, Crispin M, Ozorowski G, Ward AB, Wilson IA, Hanke T, Sliepen K, Sanders RW
NPJ Vaccines (2024) 9 pp. 74-74 [ Pubmed: 38582771 DOI: doi:10.1038/s41541-024-00862-8 ]
Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines (H5/1 GCN4)
Del Moral-Sanchez I, Wee EG, Xian Y, Lee WH, Allen JD, Torrents de la Pena A, Froes Rocha R, Ferguson J, Leon AN, Koekkoek S, Schermer EE, Burger JA, Kumar S, Zwolsman R, Brinkkemper M, Aartse A, Eggink D, Han J, Yuan M, Crispin M, Ozorowski G, Ward AB, Wilson IA, Hanke T, Sliepen K, Sanders RW
NPJ Vaccines (2024) 9 pp. 74-74 [ Pubmed: 38582771 DOI: doi:10.1038/s41541-024-00862-8 ]
Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines. H5 GCN4
Del Moral-Sanchez I, Wee EG, Xian Y, Lee WH, Allen JD, Torrents de la Pena A, Froes Rocha R, Ferguson J, Leon AN, Koekkoek S, Schermer EE, Burger JA, Kumar S, Zwolsman R, Brinkkemper M, Aartse A, Eggink D, Han J, Yuan M, Crispin M, Ozorowski G, Ward AB, Wilson IA, Hanke T, Sliepen K, Sanders RW
NPJ Vaccines (2024) 9 pp. 74-74 [ Pubmed: 38582771 DOI: doi:10.1038/s41541-024-00862-8 ]
H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting 1-1-1F05
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8tp2
Q-score: 0.541
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB
bioRxiv (2023) [ Pubmed: 37781590 DOI: doi:10.1101/2023.08.23.554525 ]
- H2 hemagglutinin (a/singapore/1/1957) in complex with rbs-targeting fab 1-1-1f05 (Complex from Influenza A virus (A/Singapore/1/1957(H2N2)))
- Light chain of fab 1-1-1f05 (11 kDa, Protein from Homo sapiens)
- Hemagglutinin (57 kDa, Protein from Homo sapiens)
- Heavy chain of fab 1-1-1f05 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1F05
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8tp3
Q-score: 0.38
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB
bioRxiv (2023) [ Pubmed: 37781590 DOI: doi:10.1101/2023.08.23.554525 ]
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- Hemagglutinin ha1 chain (38 kDa, Protein from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- H1 hemagglutinin (nc99) in complex with sa-targeting fab 1-1-1f05 (Complex from Influenza A virus (A/New Caledonia/20/1999(H1N1)))
- Light chain of fab 1-1-1f05 (11 kDa, Protein from Homo sapiens)
- Heavy chain of fab 1-1-1f05 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting Fab 1-1-1E04
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8tp4
Q-score: 0.516
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB
bioRxiv (2023) [ Pubmed: 37781590 DOI: doi:10.1101/2023.08.23.554525 ]
- H2 hemagglutinin (a/singapore/1/1957) in complex with rbs-targeting fab 1-1-1e04 (Complex from Influenza A virus (A/Singapore/1/1957(H2N2)))
- Heavy chain of fab 1-1-1e04 (14 kDa, Protein from Homo sapiens)
- Light chain of fab 1-1-1e04 (13 kDa, Protein from Homo sapiens)
- Hemagglutinin (57 kDa, Protein from Influenza A virus (A/Singapore/1/1957(H2N2)))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)